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The principal cytochrome P450 isoenzyme involved appears to generally be CYP2E1, with CYP1A2 and CYP3A4 as extra pathways. About 85% of an oral dose seems during the urine in just 24 several hours of administration, most since the glucuronide conjugate, with tiny amounts of other conjugates and unchanged drug [see OVERDOSAGE] for toxicity informati